Software
Chorus2
Design of genome-scale oligonucleotide-based probes for fluorescence in situ hybridization (FISH)
CrisprStitch
An integrated tool to fast evaluate the efficiency of CRISPR editing systems.
CRISPR-BETS
A gRNA design software for base editing knockout using stop codon.
Popera
A software specially designed for DHS identification. Github Introduction DNase I hypersensitive sites (DHSs) are regions of chromatin that are sensitive to cleavage by the...
Latest
![Chorus2 oligo datasets](/assets/images/oligo_db.png)
Chorus2 oligo datasets
Oligo datasets which host oligo sequences for Oligo-FISH. Details Introduction The oligo datasets currently host oligo sequences of nine species, including Arabidopsis, rice, maize, potato, barley, soybean, human, mouse and...
![PlantDHS](/assets/images/plantdhs.jpg)
PlantDHS
PlantDHS: a database for DNase I hypersensitive sites (DHSs) in plants.
![CAPE](/assets/images/CAPE/cape.png)
CAPE
CAPE: An efficient CRISPR-Cas12a promoter editing system for crop improvement [JBrowse preview](https://bioinfor.yzu.edu.cn/jbrowse2/cape) ## Introduction we demonstrate a **CAPE** based promoter editing and tuning pipeline for efficient production of useful quantitative...
![CAPE](/assets/images/CAPE/cape.png)
CAPE
CAPE: An efficient CRISPR-Cas12a promoter editing system for crop improvement JBrowse preview Introduction we demonstrate a CAPE based promoter editing and tuning pipeline for efficient production of useful quantitative trait...
Lab meeting
![Genome-wide cis-decoding for expression design in tomato using cistrome data and explainable deep learning](/assets/images/lab_meeting/2022-07-17.png)
Genome-wide cis-decoding for expression design in tomato using cistrome data and explainable deep learning
Abstract: In the evolutionary history of plants, variation in cis-regulatory elements (CREs) resulting in diversification of gene expression has played a central role in driving the evolution of lineage-specific traits....
![OsAAP6 functions as an important regulator of grain protein content and nutritional quality in rice](/assets/images/lab_meeting/2022-06-29.png)
OsAAP6 functions as an important regulator of grain protein content and nutritional quality in rice
Abstract: Grains from cereals contribute an important source of protein to human food, and grain protein content (GPC) is an important determinant of nutritional quality in cereals. Here we show...
![H1 linker histones silence repetitive elements by promoting both histone H3K9 methylation and chromatin compaction](/assets/images/lab_meeting/2022-06-22.png)
H1 linker histones silence repetitive elements by promoting both histone H3K9 methylation and chromatin compaction
Abstract: Nearly 50% of mouse and human genomes are composed of repetitive sequences. Transcription of these sequences is tightly controlled during development to prevent genomic instability, inappropriate gene activation and...
![Splicing-mediated activation of SHAGGY-like kinases underpinning carbon partitioning in Arabidopsis seeds](/assets/images/lab_meeting/2022-06-14.png)