Software
Chorus2
Design of genome-scale oligonucleotide-based probes for fluorescence in situ hybridization (FISH)
CrisprStitch
An integrated tool to fast evaluate the efficiency of CRISPR editing systems.
CRISPR-BETS
A gRNA design software for base editing knockout using stop codon.
Popera
A software specially designed for DHS identification. Github Introduction DNase I hypersensitive sites (DHSs) are regions of chromatin that are sensitive to cleavage by the...
Latest
Chorus2 oligo datasets
Oligo datasets which host oligo sequences for Oligo-FISH. Details Introduction The oligo datasets currently host oligo sequences of nine species, including Arabidopsis, rice, maize, potato, barley, soybean, human, mouse and...
PlantDHS
PlantDHS: a database for DNase I hypersensitive sites (DHSs) in plants.
CAPE
CAPE: An efficient CRISPR-Cas12a promoter editing system for crop improvement JBrowse preview Introduction we demonstrate a CAPE based promoter editing and tuning pipeline for efficient production of useful quantitative trait...
Lab meeting
Genome-wide cis-decoding for expression design in tomato using cistrome data and explainable deep learning
Abstract: In the evolutionary history of plants, variation in cis-regulatory elements (CREs) resulting in diversification of gene expression has played a central role in driving the evolution of lineage-specific traits....
OsAAP6 functions as an important regulator of grain protein content and nutritional quality in rice
Abstract: Grains from cereals contribute an important source of protein to human food, and grain protein content (GPC) is an important determinant of nutritional quality in cereals. Here we show...
H1 linker histones silence repetitive elements by promoting both histone H3K9 methylation and chromatin compaction
Abstract: Nearly 50% of mouse and human genomes are composed of repetitive sequences. Transcription of these sequences is tightly controlled during development to prevent genomic instability, inappropriate gene activation and...
